Product Name

MAGEC2 antibody

Documents

Description

MAGEC2 Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue, human breast cancer tissue, human liver cancer tissue.

Tested applications

ELISA, IHC

Species reactivity

Human; other species not tested.

Alternative names

Cancer/testis antigen 10 antibody; CT10 antibody; HCA587 antibody; MAGE C2 antigen antibody; MAGE E1 antigen antibody; MAGEC2 antibody; MAGEE1 antibody; melanoma antigen family C antibody; Melanoma assOCiated antigen C2 antibody

Isotype

Rabbit IgG

Preparation

This antibody was obtained by immunization of MAGEC2 recombinant protein (Accession Number: NM_016249). Purification method: Antigen affinity purified.

Clonality

Polyclonal

Formulation

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions

Store at -20℃. DO NOT ALIQUOT

Applications

Recommended Dilution:

IHC: 1:20-1:200

Validations

Immunohistochemistry of paraffin-embedded human testis tissue slide using Catalog No:112387(MAGEC2 Antibody) at dilution of 1:50 (under 10x lens)

Immunohistochemistry of paraffin-embedded human testis tissue slide using Catalog No:112387(MAGEC2 Antibody) at dilution of 1:50 (under 40x lens)

Background

Melanoma antigen family C, 2(MAGEC2, synonyms: CT10, HCA587, MAGEE1, MGC13377) is related to members of the MAGEC gene family. MAGEC2 is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and other MAGEC genes are clustered on chromosome Xq26-q27.

References

Sharma A, Bode B, Wenger RH. γ-Radiation promotes immunological recognition of cancer cells through increased expression of cancer-testis antigens in vitro and in vivo. PloS one. 6(11):e28217. 2011.
Weissferdt A, Rodriguez-Canales J, Liu H, Fujimoto J, Wistuba II, Moran CA. Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers. Human pathology. 46(3):376-83. 2015.

MAGEC2 antibody

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