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Product Name
MAG antibody
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Description
MAG Rabbit Polyclonal antibody. Positive WB detected in mouse spinal cord tissue, rat brain tissue. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 100 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GMA antibody; MAG antibody; myelin assOCiated glycoprotein antibody; S MAG antibody; SIGLEC 4A antibody; SIGLEC4A antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MAG recombinant protein (Accession Number: NM_002361). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse spinal cord tissue were subjected to SDS PAGE followed by western blot with Catalog No:112375(MAG Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:112375(MAG Antibody) at dilution of 1:200 (under 10x lens).
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:112375(MAG Antibody) at dilution of 1:200 (under 40x lens).
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Background
MAG (myelin associated glycoprotein) is a 100-kDa transmembrane glycoprotein that is a member of the SIGLEC family of proteins. MAG is localized in periaxonal Schwann cell and oligodendroglial membranes of myelin sheaths where it functions in glia-axon interactions (PMID: 17241126). It is a functional ligand for the Nogo-66 receptor (PMID: 12089450). MAG is a cell adhesion molecule for postnatal neural development and is thought to be involved in the process of myelination.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"