LSM8 antibody

LSM8 antibody

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• Material Safety Data Sheets (MSDS)

LSM8 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, HL-60 cells. Observed molecular weight by Western-blot: 11 kDa

ELISA, WB

Human,Mouse,Rat; other species not tested.

LSM8 antibody; NAA38 antibody; YJR022W antibody

Rabbit IgG

This antibody was obtained by immunization of LSM8 recombinant protein (Accession Number: NM_016200). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing[PMID:15075370]. Lsm2–Lsm8 (Lsm stands for Like Sm), binds and stabilizes the 3′ end of the spliceosomal U6 snRNA Lsm proteins facilitate the annealing of U6 snRNA with U4 snRNA in vitro and interact with the U4/U6 annealing factor Prp24, suggesting that Lsm proteins function in U4/U6 snRNP formation in vivo [PMID:15485930, 17251193].