LITAF antibody

Cat.#: 112246

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Product Information

  • Product Name
    LITAF antibody
  • Documents
  • Description
    LITAF Rabbit Polyclonal antibody. Positive IHC detected in human spleen tissue. Positive WB detected in HeLa cells, HepG2 cells. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 24 kDa
  • Tested applications
    ELISA, WB, IHC, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    FLJ38636 antibody; LITAF antibody; LPS induced TNF alpha factor antibody; p53 induced gene 7 protein antibody; PIG7 antibody; SIMPLE antibody; TP53I7 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of LITAF recombinant protein (Accession Number: NM_004862). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:112246(LITAF antibody) at dilution of 1:500

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:112246(LITAF antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human spleen using Catalog No:112246(LITAF antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human spleen using Catalog No:112246(LITAF antibody) at dilution of 1:100 (under 10x lens)

    IP Result of anti-LITAF (IP:Catalog No:112246, 4ug; Detection:Catalog No:112246 1:600) with HeLa cells lysate 1520ug.

    IP Result of anti-LITAF (IP:Catalog No:112246, 4ug; Detection:Catalog No:112246 1:600) with HeLa cells lysate 1520ug.

  • Background
    Lipopolysaccharide-induced TNF factor(LITAF) is a transcription factor that identified as a regulator of TNF-alpha gene expression. It may has a role in protein degradation pathways and in tumor necrosis factor alpha(TNF-alpha) gene expression. Also it may regulate the expression of the CCL2/MCP-1 chemokine through NFKB1.Defects in LITAF may be involved in extramammary Paget disease (EMPD) carcinogenesis

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"