Lf-CATH1 peptide

Lf-CATH1 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

PPCRGIFCRRVGSSSAIARPGKTLSTFITV

Pro-Pro-Cys-Arg-Gly-Ile-Phe-Cys-Arg-Arg-Val-Gly-Ser-Ser-Ser-Ala-Ile-Ala-Arg-Pro-Gly-Lys-Thr-Leu-Ser-Thr-Phe-Ile-Thr-Val

30

96%

Synthetic

Powder

39.0% similar to Gallinacin 3. Active against Gram-positive S. aureus (ATCC2592, IS1303, IS 1349) (MIC 1.25-10 uM), S. epidermidis (MIC 5 uM), P. acnes ATCC11827 (MIC 10.1 uM), Gram-negative P. aeruginosa (IS 1411, IS 1412, IS 1413) (MIC 10. 1 uM), E. coli (ATCC25922, IS 1334, IS 1335, IS 1342) (MIC 2.5-5.0 uM), K. pneumoniae IS 1368 (MIC 10.1 uM), and fungi C. albicans ATCC2002, C. glabrata IS0902) (MIC 1.26-5.04 uM). Lf-CATH1 was found in spleen, liver and kidney, fragile large-headed frog, fragile wart frog, Limnonectes fragilis, Hainan, China, Asia.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Yu H, Cai S, Gao J, et al. Identification and polymorphism discovery of the cathelicidins, Lf-CATHs in ranid amphibian (Limnonectes fragilis). FEBS J. 2013;280(23):6022-32.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.