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Product Name
LAT2 Polyclonal Antibody
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Description
Polyclonal antibody to LAT2
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Tested applications
WB
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Species reactivity
Human
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Alternative names
LAT2 antibody; HSPC046 antibody; LAB antibody; NTAL antibody; WBSCR15 antibody; WBSCR5 antibody; WSCR5 antibody; linker for activation of T-cells family member 2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic Peptide of human LAT2
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
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Validations
Western blot - LAT2 Polyclonal Antibody
Western blot analysis of extracts of HeLa cells, using LAT2 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"