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Product Name
LAMP1 antibody
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Description
LAMP1 Rabbit Polyclonal antibody. Positive IHC detected in human gliomas tissue, human pancreas tissue. Positive WB detected in RAW 264.7 cells. Positive IP detected in RAW 264.7 cells. Observed molecular weight by Western-blot: 120 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
CD107a antibody; LAMP 1 antibody; LAMP1 antibody; LAMPA antibody; LGP120 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of LAMP1 recombinant protein (Accession Number: NM_005561). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IP: 1:500-1:5000
IHC: 1:20-1:200
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Validations
RAW 264.7 cells were subjected to SDS PAGE followed by western blot with Catalog No:112276(CD107a Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using Catalog No:112276(CD107a Antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using Catalog No:112276(CD107a Antibody) at dilution of 1:50 (under 10x lens)
IP Result of anti-CD107a (IP:Catalog No:112276, 4ug; Detection:Catalog No:112276 1:1000) with RAW 264.7 cells lysate 1400ug.
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Background
LAMP1 (also known as CD107a) is a 120-kDa heavily glycosylated membrane protein enriched in the lysosomal membrane. LAMP1 functions to provide selectins with carbohydrate ligands. This protein has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells and may also play a role in tumor cell differentiation and metastasis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"