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Product Name
LACTB antibody
- Documents
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Description
LACTB Rabbit Polyclonal antibody. Positive IHC detected in human liver. Positive WB detected in human heart tissue, HeLa cells. Observed molecular weight by Western-blot: 55kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
LACTB antibody; MRPL56 antibody; lactamase antibody; beta antibody; G24 antibody; FLJ14902 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of LACTB recombinant protein (Accession Number: NM_032857). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:112264(LACTB antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human liver using Catalog No:112264(LACTB antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human liver using Catalog No:112264(LACTB antibody) at dilution of 1:100 (under 40x lens)
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Background
LACTB is also named as MRPL56,whic is a component of the large subunit of the mitochondrial ribosome that is encoded by the nuclear genome.LACTB is a mammalian active-site serine protein that has evolved from a bacterial penicillin-binding protein.It promotes intramitochondrial membrane organization and micro-compartmentalization through polymerization(PMID:19858488). Northern blot analysis of mouse tissues detected expression at high levels in liver, heart, and skeletal muscle, with lower levels in kidney, testis, brain, lung, and spleen(PMID:11707067).This antibody is specific to LACTB.
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