KRT33B antibody

Cat.#: 112130

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Product Information

  • Product Name
    KRT33B antibody
  • Documents
  • Description
    KRT33B Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells, human brain tissue. Positive IHC detected in human prostate cancer. Observed molecular weight by Western-blot: 46 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    human; other species not tested.
  • Alternative names
    KRT33B antibody; hHa3 II antibody; KRTHA3A antibody; keratin 33B antibody; Ha 3II antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of KRT33B recombinant protein (Accession Number: NM_002279). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:112130(KRT33B antibody) at dilution of 1:800

    MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:112130(KRT33B antibody) at dilution of 1:800

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:112130(KRT33B antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:112130(KRT33B antibody) at dilution of 1:50 (under 10x lens)

  • Background
    Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated, tissue specific, and varies according to cell-state. Type I keratins consist of acidic, low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral, high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18). Keratin 33 belongs to type I keratin and is found in hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.
  • References
    • Ma YM, Wu KJ, Dang Q. Testosterone regulates keratin 33B expression in rat penis growth through androgen receptor signaling. Asian journal of andrology. 16(6):817-23. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"