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Product Name
KRT10-specific antibody
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Description
KRT10-specific Rabbit Polyclonal antibody. Positive IHC detected in human lung cancer.
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Tested applications
ELISA, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
KRT10 antibody; K10 antibody; Cytokeratin 10 antibody; CK 10 antibody; keratin 10 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_000421). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:112126(KRT10-specific antibody) at dilution of 1:200 (under 10x lens)
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:112126(KRT10-specific antibody) at dilution of 1:200 (under 40x lens)
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Background
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. As a type I keratin, keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia. This antibody is specifically against KRT10.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"