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Product Name
KLK3/PSA antibody
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Description
KLK3/PSA Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human prostate cancer tissue.
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
APS antibody; Gamma seminoprotein antibody; hK3 antibody; Kallikrein 3 antibody; kallikrein related peptidase 3 antibody; KLK2A1 antibody; KLK3 antibody; P 30 antigen antibody; Prostate specific antigen antibody; PSA antibody; Semenogelase antibody; Seminin antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of KLK3/PSA recombinant protein (Accession Number: NM_001648). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:112109(KLK3,PSA antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:112109(KLK3,PSA antibody) at dilution of 1:50 (under 40x lens)
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:112109(KLK3,PSA Antibody) at dilution of 1:1000
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Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. kallikrein-related peptidase 3, which is also called PSA (prostate-specific antigen) in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. KLK3 has 5 isoforms produced by alternative splicing.
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