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Product Name
KLHL42 Polyclonal Antibody
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Description
Polyclonal antibody to KLHL42
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Tested applications
IHC
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Species reactivity
Human, Mouse
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Alternative names
KLHL42 antibody; Ctb9 antibody; KLHDC5 antibody; kelch-like protein 42 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-505 of human KLHL42 (NP_065833.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IHC 1:50 - 1:200
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Validations
Immunohistochemistry - KLHL42 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human liver using KLHL42 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - KLHL42 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human gastric cancer using KLHL42 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - KLHL42 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse testis leydig using KLHL42 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - KLHL42 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse kidney using KLHL42 antibody at dilution of 1:100 (40x lens).
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Background
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"