KLF6 antibody

KLF6 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

KLF6 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, human placenta tissue, mouse colon tissue, mouse testis tissue, mouse thymus tissue, PC-3 cells. Positive IHC detected in human testis tissue. Observed molecular weight by Western-blot: 42-45kd

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

B cell derived protein 1 antibody; COPEB antibody; CPBP antibody; DKFZp686N0199 antibody; GBF antibody; KLF6 antibody; Krueppel like factor 6 antibody; Kruppel like factor 6 antibody; PAC1 antibody; Proto oncogene BCD1 antibody; ST12 antibody; Transcription factor Zf9 antibody; ZF9 antibody

Rabbit IgG

This antibody was obtained by immunization of KLF6 recombinant protein (Accession Number: NM_001008490). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

KLF6(krupple-like factor 6) is a zinc finger transcription factor and tumor suppressor with biological activities and transcriptional targets in growing range. It is highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon. One key target gene of KLF6 in endoglin, which is a homodimeric cell membrane glycoprotein and TGF-β auxiliary receptor, owns a pro-angiogenic role in endothelial cells and is also involved in malignant progression. Also KLF6 induces apoptosis in prostate cancer cells through upregulation of ATF3. KLF6 was normal detected as a 46kDa protein, which is larger than translation product(32kDa), because of post-translational modification including both phosphorylation and glycosylation. This antibody raise against the full length of KLF6 gene of human origin, and can recognize both of KLF6, included KLF6(~32kDa), p-KLF6(~35-46kDa). Otherwise, there may be a non-specific band(50kDa) showed in detection