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Product Name
KIR2DS4 antibody
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Description
KIR2DS4 Rabbit Polyclonal antibody. Positive WB detected in HL-60 cells, Jurkat cells. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 33 kDa
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Tested applications
ELISA, WB, IF
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Species reactivity
Human; other species not tested.
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Alternative names
CD158I antibody; KIR1D antibody; KIR2DS4 antibody; KIR412 antibody; KKA3 antibody; MHC class I NK cell receptor antibody; NKAT 8 antibody; NKAT8 antibody; p58 NK receptor CL 39/CL 17 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of KIR2DS4 recombinant protein (Accession Number: NM_012314). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IF: 1:10-1:100
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Validations
HL-60 cells were subjected to SDS PAGE followed by western blot with Catalog No:112061(KIR2DS4 antibody) at dilution of 1:500
Immunofluorescent analysis of HepG2 cells, using KIR2DS4 antibody Catalog No:112061 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
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Background
KIR2DS4 (also known as CD158i) is a member of the killer cell immunoglobulin-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. KIRs are mainly involved in inhibiting NK killing (inhibitory KIRs) via interaction with MHC class I molecules. KIR2DS4 has been reported to be an activating KIR and recognize the HLA-Cw4 protein.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"