Kir2.1 antibody

Kir2.1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Kir2.1 Rabbit Polyclonal antibody. Positive WB detected in A549 cells. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 50kd,60kd

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

HHBIRK1 antibody; HHIRK1 antibody; hIRK1 antibody; IRK 1 antibody; IRK1 antibody; KCNJ2 antibody; Kir2.1 antibody; LQT7 antibody; SQT3 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_000891). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

KCNJ2, also named as HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7 and SQT3, belongs to the inward rectifier-type potassium channel family. KCNJ2 probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ2 can be blocked by extracellular barium or cesium. Defects in KCNJ2 are the cause of long QT syndrome type 7 (LQT7). Defects in KCNJ2 are the cause of short QT syndrome type 3 (SQT3). The antibody recognizes the C-term of KCNJ2.