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Product Name
Kininogen 1 antibody
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Description
Kininogen 1 Mouse Monoclonal antibody. Positive WB detected in human blood tissue. Positive IHC detected in human breast cancer tissue. Observed molecular weight by Western-blot: 60 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
BDK antibody; Fitzgerald factor antibody; HMWK antibody; Ile Ser Bradykinin Bradykinin antibody; Kallidin I Lysyl bradykinin antibody; kininogen 1 antibody; KNG antibody; KNG1 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of Kininogen 1 recombinant protein (Accession Number: NM_000893). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:2000-1:20000
IHC: 1:20-1:200
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Validations
human blood tissue were subjected to SDS PAGE followed by western blot with Catalog No:107363(KNG1 antibody) at dilution of 1:5000
Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:107363(KNG1 Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:107363(KNG1 Antibody) at dilution of 1:50
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Background
Kininogens are inhibitors of thiol proteases. Kininogen 1 plays important role in Kinin-kallikrein system. This gene is translated into High-molecular weight kininogen (HMWK) and low-molecular weight kininogen (LMWK) after alternative splicing. HMWK is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation, and has no intrinsic catalytic activity. LMWK is produced locally by numerous tissues, and secreted together with tissue kallikrein.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"