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Product Name
KHSRP Polyclonal Antibody
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Description
Polyclonal antibody to KHSRP
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Tested applications
WB, IHC, IF
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Species reactivity
Human
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Alternative names
KHSRP antibody; FBP2 antibody; FUBP2 antibody; KSRP antibody; KH-type splicing regulatory protein antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human KHSRP
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:10 - 1:50 -
Validations
Western blot - KHSRP Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using KHSRP antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"