KDM4A antibody

KDM4A antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

KDM4A Rabbit Polyclonal antibody. Positive WB detected in NIH/3T3 cells, MCF-7 cells. Observed molecular weight by Western-blot: 55 kDa

ELISA, WB

Human, Mouse; other species not tested.

JHDM3A antibody; JMJD2 antibody; JMJD2A antibody; KDM4A antibody; KIAA0677 antibody; lysine (K) demethylase 4A antibody; Lysine specific demethylase 4A antibody

Rabbit IgG

This antibody was obtained by immunization of KDM4A recombinant protein (Accession Number: XM_005271355). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

KDM4A also named as JHDM3A, JMJD2, or KIAA0677 is a 1066 amino acid protein, which contains one JmjC domain, two Tudor domains and two PHD-type zinc fingers. KDM4A localizes in nucleus and belongs to the JHDM3 histone demethylase family. KDM4A is histone de-methylase that specifically demethylates Lys 9 and Lys 36 residues of Histone H3, thereby playing a central role in histone code. JMJD2A demethylation of lysine residues will generate formaldehyde and succinate. KDM4A also participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. JMJD2A is a ubiquitously expressed nuclear protein. KDM4A exists as two isoforms. The short isoform of KDM4A in which the N-terminal demethylase domains has been deleted. The molecular weight of short isoform is 55Da.