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  • KCNU1 Polyclonal Antibody

KCNU1 Polyclonal Antibody

Cat.#: 166595

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Product Information

  • Product Name
    KCNU1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to KCNU1
  • Tested applications
    WB
  • Species reactivity
    Rat
  • Alternative names
    KCNU1 antibody; KCNMC1 antibody; KCa5 antibody; KCa5.1 antibody; Kcnma3 antibody; Slo3 antibody; potassium channel subfamily U member 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 920-1149 of human KCNU1 (NP_001027006.2).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - KCNU1 Polyclonal Antibody

    Western blot - KCNU1 Polyclonal Antibody

    Western blot analysis of extracts of rat testis, using KCNU1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

  • Background
    Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May represent the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"