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  • KCNN3 Polyclonal Antibody
  • KCNN3 Polyclonal Antibody

KCNN3 Polyclonal Antibody

Cat.#: 166573

Special Price 174.2 USD

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Product Information

  • Product Name
    KCNN3 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to KCNN3
  • Tested applications
    WB, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    KCNN3 antibody; KCa2.3 antibody; SK3 antibody; SKCA3 antibody; hSK3 antibody; potassium calcium-activated channel subfamily N member 3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 237-426 of human KCNN3 (NP_740752.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:1000
    IF 1:50 - 1:100
  • Validations

    Western blot - KCNN3 Polyclonal Antibody

    Western blot - KCNN3 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using KCNN3 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit .Exposure time: 60s.

    Immunofluorescence - KCNN3 Polyclonal Antibody

    Immunofluorescence - KCNN3 Polyclonal Antibody

    Immunofluorescence analysis of U2OS cells using KCNN3 antibody . Blue: DAPI for nuclear staining.

  • Background
    Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"