KCNK18 antibody

Cat.#: 111972

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Product Information

  • Product Name
    KCNK18 antibody
  • Documents
  • Description
    KCNK18 Rabbit Polyclonal antibody. Positive WB detected in A431 cells, A375 cells, MCF-7 cells. Observed molecular weight by Western-blot: 44 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    K2p18.1 antibody; KCNK18 antibody; TRESK antibody; TRESK 2 antibody; TRESK2 antibody; TRIK antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of KCNK18 recombinant protein (Accession Number: NM_181840). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

  • Validations

    A431 cells were subjected to SDS PAGE followed by western blot with Catalog No:111972(KCNK18 Antibody) at dilution of 1:1000

    A431 cells were subjected to SDS PAGE followed by western blot with Catalog No:111972(KCNK18 Antibody) at dilution of 1:1000

  • Background
    KCNK18, also named as TRESK and TRIK, is an outward rectifying potassium channel which produces rapidly activating outward rectifier K+ currents. It may function as background potassium channel that sets the resting membrane potential. KCNK18 is inhibited by arachidonic acid and other naturally occurring unsaturated free fatty acids. KCNK18 channel activity is enhanced by volatile anesthetics, such as isoflurane. The gene of KCNK18 maps to chromosome 10q26.11, and encodes a 384-amino acid protein with a predicted unmodified molecular weight of 44 kDa. This antibody can be used to detect endogenous KCNK18, however, the reason for the additional band of 130-140 kDa is still unknown.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"