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Product Name
KCNJ13 Polyclonal Antibody
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Description
Polyclonal antibody to KCNJ13
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Tested applications
WB, IHC
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Species reactivity
Human
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Alternative names
KCNJ13 antibody; KIR1.4 antibody; KIR7.1 antibody; LCA16 antibody; SVD antibody; inward rectifier potassium channel 13 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human KCNJ13
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
IHC 1:50 - 1:100 -
Validations
Western blot - KCNJ13 Polyclonal Antibody
Western blot analysis of extracts of MDA-MB-435u00a0 cells, using KCNJ13 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"