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Product Name
KCNH2 Polyclonal Antibody
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Description
Polyclonal antibody to KCNH2
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
KCNH2 antibody; ERG-1 antibody; ERG1 antibody; H-ERG antibody; HERG antibody; HERG1 antibody; Kv11.1 antibody; LQT2 antibody; SQT1 antibody; potassium voltage-gated channel subfamily H member 2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human KCNH2
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - KCNH2 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using KCNH2 antibody at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit .Exposure time: 30s.
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Background
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr).; Isoform A-USO: Has no channel activity by itself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.; Isoform B-USO: Has no channel activity by itself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"