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Product Name
KCNB1-Specific antibody
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Description
KCNB1-Specific Rabbit Polyclonal antibody. Positive IF detected in SH-SY5Y cells, HEK-293 cells.
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Tested applications
ELISA, IF
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Species reactivity
Human; other species not tested.
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Alternative names
DRK1 antibody; h DRK1 antibody; KCNB1 antibody; KV2.1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_004975). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IF: 1:10-1:100
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Validations
Immunofluorescent analysis of SH-SY5Y cells using Catalog No:111926(KCNB1-Specific Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
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Background
KCNB1, also named as DRK1, KV2.1, and h-DRK1, belongs to the potassium channel family and B (Shab) subfamily. KCNB1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. The antibody is specific to KCNB1.
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References
- Liu W, Wang D, Song K. Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1Inhibition of 15-lipoxygenase (15-LOX) reverses hypoxia-induced down-regulation of potassium channels Kv1.5 and Kv2.1. International journal of clinical and experimental medicine. 7(11):4147-53. 2014.
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