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Product Name
KAT6A Polyclonal Antibody
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Description
Polyclonal antibody to KAT6A
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Tested applications
WB, IHC, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
KAT6A antibody; MOZ antibody; MRD32 antibody; MYST-3 antibody; MYST3 antibody; RUNXBP2 antibody; ZC2HC6A antibody; ZNF220 antibody; lysine acetyltransferase 6A antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human KAT6A (NP_001092883.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200 -
Validations
Western blot - KAT6A Polyclonal Antibody
Western blot analysis of extracts of 293T cells, using KAT6A antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 10s.
Immunofluorescence - KAT6A Polyclonal Antibody
Immunofluorescence analysis of NIH/3T3 cells using KAT6A antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence - KAT6A Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using KAT6A antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Background
Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"