-
Product Name
Kallikrein 11 antibody
- Documents
-
Description
Kallikrein 11 Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells, HeLa cells, PC-3 cells, Y79 cells. Positive IHC detected in human prostate cancer tissue, human brain tissue. Positive IF detected in PC-3 cells. Observed molecular weight by Western-blot: 40kd
-
Tested applications
ELISA, WB, IHC, IF
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
Hippostasin antibody; hK11 antibody; Kallikrein 11 antibody; KLK11 antibody; PRSS20 antibody; Serine protease 20 antibody; TLSP antibody; Trypsin like protease antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of Kallikrein 11 recombinant protein (Accession Number: NM_001136032). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:10-1:100
-
Validations
MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:111902(KLK11 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:111902(KLK11 antibody) at dilution of 1:200 (under 40x lens)
Immunofluorescent analysis of PC-3 cells using Catalog No:111902(KLK11 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
-
Background
KLK11(Kallikrein-11) is also named as PRSS20, TLSP and belongs to the peptidase S1 family and Kallikrein subfamily. It is a multifunctinal protease cleaving several substrates for kallikrein and trypsin and involved in normal physiology processes in bronchus. This full length protein has a signal peptide, a propeptide and four glycosylation sites. It has 4 isoforms produced by alternative splicing with the molecular weight of 31 kDa, 27 kDa,34 kDa and 30 kDa.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"