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Product Name
Mouse Junctional Adhesion Molecule C (His Tag) recombinant protein
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Description
Participates in cell-cell adhesion. It is a counter-receptor for ITGAM mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN) (By similarity). The soluble form is a mediator of angiogenesis.
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Protein name
Junctional adhesion molecule C
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Protein short names
JCAM3; 1110002N23RIK; UNQ859/PRO1868; JAM-2; JAM3; C85515; JAM-3; JAMC; FLJ14529; JAM-C
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Uniprot ID
Q9D8B7
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Gene Name
Jam3
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse JAM3 (NP_075766.1) extracellular domain (Met 1-Asn 241) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse JAM3 comprises 221 amino acids and has a predicted molecular mass of 25 kDa. As a result of glycosylation, the apparent molecular mass of rm JAM3 is approximately 30-35 kDa in SDS-PAGE under reducing conditions.
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Purity
> 94 % as determined by SDS-PAGE
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Validations
Mouse JAM3 / JAM-C Protein (His Tag) SDS-PAGE
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