-
Product Name
IYD antibody
- Documents
-
Description
IYD Rabbit Polyclonal antibody. Positive WB detected in human liver tissue. Observed molecular weight by Western-blot: 33kd
-
Tested applications
ELISA, WB
-
Species reactivity
Human; other species not tested.
-
Alternative names
C6orf71 antibody; DEHAL1 antibody; dJ422F24.1 antibody; Iodotyrosine dehalogenase 1 antibody; iodotyrosine deiodinase antibody; IYD antibody; IYD 1 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of IYD recombinant protein (Accession Number: NM_203395). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
-
Validations
human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:111877(IYD antibody) at dilution of 1:1000
-
Background
IYD(Iodotyrosine dehalogenase 1) is also named as C6orf71, DEHAL1 and belongs to the nitroreductase family. It is a transmembrane protein that deiodinates mono-and di-iodotyrosines (MIT, DIT) and recycles iodine, a scarce element in the environment, for the efficient synthesis of thyroid hormone. This protein has 6 isoforms produced by alternative splicing.
-
References
- Shimizu R, Yamaguchi M, Uramaru N. Structure-activity relationships of 44 halogenated compounds for iodotyrosine deiodinase-inhibitory activity. Toxicology. 314(1):22-9. 2013.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"