ITPKB Rabbit Polyclonal antibody. Positive IHC detected in human cervical cancer tissue. Positive WB detected in mouse brain tissue, K-562 cells, mouse lung tissue, mouse thymus tissue, rat brain tissue. Observed molecular weight by Western-blot: 102-110 kDa
ELISA, WB, IHC
Human, Mouse, Rat; other species not tested.
InsP 3 kinase B antibody; IP3 3 kinase B antibody; IP3K antibody; IP3K B antibody; IP3KB antibody; ITPKB antibody; PIG37 antibody
This antibody was obtained by immunization of ITPKB recombinant protein (Accession Number: NM_001388404). Purification method: Antigen affinity purified.
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20℃. DO NOT ALIQUOT
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:111958(ITPKB antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using Catalog No:111958(ITPKB Antibody) at dilution of 1:50 (under 40x lens)
Inositol 1,4,5-trisphosphate 3-kinase isoform B (IITPKB) is also named as IP3KB and possesses important roles in the development of immune cells. IP3KB can be targeted to multiple cellular compartments, among them nuclear localization and binding in close proximity to the plasma membrane. The B isoform is the only IP3K that is almost ubiquitously expressed in mammalian cells(PMID:21148483).Three isoforms of IP3KB occur in mammals, which are distinguished by different molecular masses, sensitivity to Ca2+/CaM(calmodulin), intracellular distribution and tissue expression (PMID:16173920).
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