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Product Name
ITM2A antibody
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Description
ITM2A Rabbit Polyclonal antibody. Positive IHC detected in human liver.
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Tested applications
ELISA, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
ITM2A antibody; BRICD2A antibody; integral membrane protein 2A antibody; E25A antibody; Protein E25 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_004867). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human liver using Catalog No:111953(ITM2A antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human liver using Catalog No:111953(ITM2A antibody) at dilution of 1:50 (under 40x lens)
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Background
ITM2A, also named BRICD2A and E25A, is a member of type II integral membrane (ITM2) protein family. ITM2A expression is high in osteogenic and lymphoid tissues, while both ITM2B and ITM2C are expressed in brain. There are 5 articles specifically referring to this gene in PubMed. Proteins are expected to localize in various compartments (cytoplasm, integral to membrane). No phenotype has yet been reported to our knowledge: this gene's in vivo function is yet unknown.
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References
- Tuomela S, Salo V, Tripathi SK. Identification of early gene expression changes during human Th17 cell differentiation. Blood. 119(23):e151-60. 2012.
- Kihara M, Kiyoshima T, Nagata K. Itm2a expression in the developing mouse first lower molar, and the subcellular localization of Itm2a in mouse dental epithelial cells. PloS one. 9(7):e103928. 2014.
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