IREB2 Polyclonal Antibody

IREB2 Polyclonal Antibody

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• Material Safety Data Sheets (MSDS)

Polyclonal antibody to IREB2

IF

Human

IREB2 antibody; ACO3 antibody; IRP2 antibody; IRP2AD antibody; iron-responsive element-binding protein 2 antibody

Rabbit IgG

Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human IREB2 (NP_004127.1).

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.

IF 1:20 - 1:50

RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.