IP6K2 antibody

IP6K2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

IP6K2 Rabbit Polyclonal antibody. Positive WB detected in human adrenal gland tissue, human heart tissue, K-562 cells. Observed molecular weight by Western-blot: 49kd

ELISA, WB

Human,Mouse,Rat; other species not tested.

IHPK2 antibody; InsP6 kinase 2 antibody; IP6K2 antibody; P(i) uptake stimulator antibody; PiUS antibody

Rabbit IgG

This antibody was obtained by immunization of IP6K2 recombinant protein (Accession Number: XM_017006585). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

IP6K2(Inositol hexakisphosphate kinase 2) is also named as IHPK2, PiUS and belongs to the inositol phosphokinase (IPK) family. It converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5) and and mediates apoptotic cell death via its translocation from the nucleus to the cytoplasm(PMID:21652713). IP6K2 regulates TP53 and protein kinase AKT signaling, and its aberrant increase in cells has been implicated in apoptosis and insulin resistance(PMID:21262846). It has 6 isoforms produced by alternative splicing. This antibody recognizes the others except the 8 kDa isoform of IP6K2.