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Product Name
Human MMP-1/MMP1 (His Tag) recombinant protein
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Description
Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
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Protein name
Interstitial collagenase
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Protein short names
CLGN; MMP13]; MMP-13; MMP1; CLG
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Uniprot ID
Q53G95
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Gene Name
MMP1; CLG
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the pro form of human MMP1 enzyme (NP_002412.1) precursor (Met 1-Asn 469) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The secreted recombinant human MMP1 comprises 461 amino acids migrates as an approximately 50-55 kDa band as estimated in SDS-PAGE under reducing conditions.
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Purity
> 96 % as determined by SDS-PAGE
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Activity
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2, R&D System, Cat#ES010. The specific activity is >70 pmoles/min/μg.
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Validations
Human MMP1 Protein (His Tag) SDS-PAGE
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