Rat IL20RB (Fc Tag) recombinant protein

Rat IL20RB (Fc Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20.

Interleukin 20 receptor beta IL-20R2

MGC130209; AV228068; FNDC6; HCG_2022374; IL-20R2; IL-20R-BETA; IL-20 RECEPTOR SUBUNIT BETA; IL-20RB; IL20R2; FIBRONECTIN TYPE III DOMAIN CONTAINING 6; INTERLEUKIN-20 RECEPTOR II; INTERLEUKIN-20 RECEPTOR SUBUNIT BETA; GM186; DIRS1; MGC34923

B8K1X9

Il20rb

Human Cells

A DNA sequence encoding the rat IL20RB (B8K1X9) (Met1-Pro227) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Rat

The recombinant rat IL20RB/Fc is a disulfide-linked homodimer. The reduced monomer comprises 447 amino acids and has a predicted molecular mass of 50.2 kDa. The apparent molecular mass of the protein is approximately 61 kDa in SDS-PAGE under reducing conditions.

> 70 % as determined by SDS-PAGE