Cynomolgus IL20RB (Fc Tag) recombinant protein

Cynomolgus IL20RB (Fc Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20.

IL-20R2; FNDC6; HCG_2022374; MGC130209; AV228068; IL20R2; FIBRONECTIN TYPE III DOMAIN CONTAINING 6; IL-20R-BETA; IL-20RB; IL-20 RECEPTOR SUBUNIT BETA; DIRS1; MGC34923; INTERLEUKIN-20 RECEPTOR II; INTERLEUKIN-20 RECEPTOR SUBUNIT BETA; GM186

G7MJP8

Human Cells

A DNA sequence encoding the cynomolgus IL20RB (XP_005545913.1) (Asp30-Ala230) was expressed with the Fc region of human IgG1 at the C-terminus.

Cynomolgus

The recombinant cynomolgus IL20RB consists of 439 amino acids and predicts a molecular mass of 49.2 kDa.

> 90 % as determined by SDS-PAGE.