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Product Name
Mouse IL18BP / IL18BPa (His Tag) recombinant protein
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Description
Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response (By similarity).
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Protein name
Interleukin-18-binding protein
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Protein short names
IL18BP; IL-18BP; IL18BPA; IGIFBP; MC54L
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Uniprot ID
Q9Z0M9
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Gene Name
Il18bp; Igifbp
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding mouse IL18BP (NP_034661.1) (Met 1-Ala 193) precursor was expressed with the polyhistide tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse IL18BP comprises 176 amino acids and has a predicted molecular mass of 19.4 kDa. In SDS-PAGE under reducing conditions, rm IL18BP migrates between 35-50 kDa due to different glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its ability to bind biotinylated Cynomolgus IL18 in functional ELISA.
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Validations
Mouse IL18BP Protein (His Tag) SDS-PAGE
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