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Human IFNGR1/CD119 (His & Fc Tag) recombinant protein

Cat.#: 502676

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Product Information

  • Product Name
    Human IFNGR1/CD119 (His & Fc Tag) recombinant protein
  • Documents
  • Description
    Receptor for interferon gamma. Two receptors bind one interferon gamma dimer.
  • Protein name
    Interferon gamma receptor 1
  • Protein short names
    IFNGR; IFNGR1; IMD27B; CD119; NKTAR; IFN-GAMMAR; IFGR; FLJ45734; RP3-503F13.3; IMD27A
  • Uniprot ID
    P15260
  • Gene Name
    IFNGR1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain (Met 1-Gly 245) of human IFN-? receptor 1 pre-protein (NP_000407.1) was fused with C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IFN-?R1/Fc is a disulfide-linked homodimeric Protein after removal of the signal peptide. The reduced monomer consists of 475 amino acids and predicts a molecular mass of 53.7 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rhIFN-?R1/Fc is approximately 75-80 kDa due to the glycosylation.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to inhibit rhIFN­γ mediated protection of WISH cells infected with vesicular stomatitis virus(VSV).
    The ED50 for this effect is typically 0.4-2 μg/mL.
  • Validations

    Human IFNGR1 / CD119 Protein (His & Fc Tag) SDS-PAGE

    Human IFNGR1 / CD119 Protein (His & Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"