-
Product Name
Mouse IFNB1/IFN-beta/Interferon beta (Fc Tag) recombinant protein
- Documents
-
Description
Has antiviral, antibacterial and anticancer activities.
-
Protein name
Interferon beta
-
Protein short names
IFN-BETA; IFN BETA; IFF; IFNB; RP23-19G2.2; IFB; IFNB1
-
Uniprot ID
P01575
-
Gene Name
Ifnb1; Ifb; Ifnb
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain of mouse IFNB1 (P01575) (Met 1-Asn 182) was fused with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Mouse
-
Molecular weight
The secreted recombinant mouse IFNB1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 402 amino acids and has a calculated molecular mass of 46.7 kDa. As a result of glycosylation, the apparent molecular mass of rmIFNB1/Fc monomer is approximately 58 kDa in SDS-PAGE under reducing conditions.
-
Purity
> 92 % as determined by SDS-PAGE
-
Activity
Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV).
The ED50 for this effect is typically 10-50 pg/mL. -
Validations
Mouse IFNB1 / IFN-beta / Interferon beta Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"