Mouse IFNB1/IFN-beta/Interferon beta (Fc Tag) recombinant protein

Cat.#: 502230

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Product Information

  • Product Name
    Mouse IFNB1/IFN-beta/Interferon beta (Fc Tag) recombinant protein
  • Documents
  • Description
    Has antiviral, antibacterial and anticancer activities.
  • Protein name
    Interferon beta
  • Protein short names
    IFN-BETA; IFN BETA; IFF; IFNB; RP23-19G2.2; IFB; IFNB1
  • Uniprot ID
    P01575
  • Gene Name
    Ifnb1; Ifb; Ifnb
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain of mouse IFNB1 (P01575) (Met 1-Asn 182) was fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The secreted recombinant mouse IFNB1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 402 amino acids and has a calculated molecular mass of 46.7 kDa. As a result of glycosylation, the apparent molecular mass of rmIFNB1/Fc monomer is approximately 58 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Activity
    Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV).
    The ED50 for this effect is typically 10-50 pg/mL.
  • Validations

    Mouse IFNB1 / IFN-beta / Interferon beta Protein (Fc Tag) SDS-PAGE

    Mouse IFNB1 / IFN-beta / Interferon beta Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"