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Product Name
Human IFNA10 (Fc Tag) recombinant protein
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Description
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
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Protein name
Interferon alpha-10
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Protein short names
IFN-ALPHAC; MGC119879; MGC119878; IFA10
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Uniprot ID
P01566
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Gene Name
IFNA10
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human IFNA10 (P01566) (Cys 24-Asp 189) was fused with the Fc region of human IgG1 at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human IFNA10/Fc chimera is a disulfide-linked homodimer. The reduced monomer comprises 427 amino acids with a predicted molecular mass of 48 kDa. AsrhIFNA10/Fc monomer migrates as an approximately 50 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Activity
Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitisvirus (VSV).
The ED50 for this effect is 20-80 pg/mL. -
Validations
Human Interferon alpha 10 / IFNA10 Protein (Fc Tag) SDS-PAGE
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