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Product Name
Rat IFN-alpha / IFNA1 / IFN (His Tag) recombinant protein
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Description
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
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Protein name
Interferon alpha-1
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Protein short names
INTERFERON ALPHA-1; IFNA ; INTERFERON ALPHA-D; IFN-ALPHA-1/13; IFN-ALPHA; INTERFERON ALPHA FAMILY GENE 1; RP23-360M23.1; IFL; LEIF D; INTERFERON ALPHA-1/13; INTERFERON ALPHA 1B; IFN-ALPHA 1B; MGC138505; IFN-ALPHA-1; IFN; IFN-ALPHAD; INTERFERON-ALPHA1; IFNA13; IFA1; MGC138507; MGC138207
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Uniprot ID
P05011
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Gene Name
Ifna1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat IFNA1 (P05011) (Met1-Ser192) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat IFNA1 comprises 180 amino acids and predicts a molecular mass of 20.9 kDa. The apparent molecular mass of the rat IFNA1 is approximately 20-25 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 99 % as determined by SDS-PAGE
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Activity
Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV).
The ED50 for this effect is typically 4-20 ng/mL. -
Validations
Rat IFN-alpha / IFNA1 / IFN Protein (His Tag) SDS-PAGE
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