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Mouse IGFBP4 (His Tag) recombinant protein

Cat.#: 500242

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Special Price 621.5 USD

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Product Information

  • Product Name
    Mouse IGFBP4 (His Tag) recombinant protein
  • Documents
  • Description
    IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • Protein name
    Insulin-like growth factor-binding protein 4
  • Protein short names
    BP-4; DEB2; HT29-IGFBP; IBP4; IGFBP-4; AI875747; IGFBP4; RP23-333D2.6
  • Uniprot ID
    P47879
  • Gene Name
    Igfbp4; Igfbp-4
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain (Met 1-Glu 254) of mouse IGFBP4 (NP_034647.1) precursor was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Mouse
  • Molecular weight
    The secreted recombinant mouse IGFBP4 consists of 244 amino acids and has a calculated molecular mass of 27.2 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 38 kDa protein in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured in a serumfree cell proliferation assay using MCF7 human breast adenocarcinoma cells (Karey, K.P. et al. 1988, Cancer Research 48: 4083.). The ED50 for this effect is typically 0.1-0.6 μg/ml.
  • Validations

    Mouse IGFBP4 Protein (His Tag) SDS-PAGE

    Mouse IGFBP4 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"