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Human IGF2BP2 (His & GST Tag) recombinant protein

Cat.#: 502543

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Product Information

  • Product Name
    Human IGF2BP2 (His & GST Tag) recombinant protein
  • Documents
  • Description
    RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts.
  • Protein name
    Insulin-like growth factor 2 mRNA-binding protein 2
  • Protein short names
    C330012H03RIK; NEILSEN; P62; IMP2; VICKZ2; IGF2BP2; RP23-50H13.1; IMP-2
  • Uniprot ID
    Q9Y6M1
  • Gene Name
    IGF2BP2; IMP2; VICKZ2
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human IGF2BP2 isoform 1 (Q9Y6M1-2) (Met 1-Lys 599) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IGF2BP2/GST chimera consists of 836 amino acids and has a calculated molecular mass of 94 kDa. It migrates as an approximately 90 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 76 % as determined by SDS-PAGE
  • Validations

    Human IGF2BP2 / IMP2 / p62 Protein (His & GST Tag) SDS-PAGE

    Human IGF2BP2 / IMP2 / p62 Protein (His & GST Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"