Human IGF2BP2/IMP2/VICKZ2 (His tag) recombinant protein

Cat.#: 519522

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Product Information

  • Product Name
    Human IGF2BP2/IMP2/VICKZ2 (His tag) recombinant protein
  • Documents
  • Description
    Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.
  • Protein name
    insulin like growth factor 2 mRNA binding protein 2(IGF2BP2)
  • Protein short names
    IMP2; VICKZ2
  • Uniprot ID
    Q9Y6M1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human IGF2BP2/IMP2/VICKZ2 Met1-Thr220 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human IGF2BP2/IMP2/VICKZ2 (His tag) recombinant protein

    Human IGF2BP2/IMP2/VICKZ2 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"