-
Product Name
Human IGF2BP2/IMP2/VICKZ2 (His tag) recombinant protein
- Documents
-
Description
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.
-
Protein name
insulin like growth factor 2 mRNA binding protein 2(IGF2BP2)
-
Protein short names
IMP2; VICKZ2
-
Uniprot ID
Q9Y6M1
-
Source/Expression Host
E.coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human IGF2BP2/IMP2/VICKZ2 Met1-Thr220 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human IGF2BP2/IMP2/VICKZ2 (His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"