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Product Name
Insulin antibody
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Description
Insulin Mouse Monoclonal antibody. Positive IHC detected in human pancreas tissue, mouse pancreas tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
ILPR antibody; INS antibody; Insulin antibody; IRDN antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of Insulin recombinant protein (Accession Number: NM_001185097). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:500-1:5000
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Validations
Immunohistochemistry of paraffin-embedded human pancreas tissue slide using Catalog No:107350(Insulin Antibody) at dilution of 1:5000 (under 10x lens).
Immunohistochemistry of paraffin-embedded human pancreas tissue slide using Catalog No:107350(Insulin Antibody) at dilution of 1:5000 (under 40x lens).
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Background
Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"