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Product Name
Importin beta antibody
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Description
Importin beta Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue. Positive WB detected in mouse brain tissue, A2780 cells, HeLa cells, HT-1080 cells, rat brain tissue. Observed molecular weight by Western-blot: 90-97 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
IMB1 antibody; Impnb antibody; Importin 90 antibody; Importin subunit beta 1 antibody; IPO1 antibody; IPOB antibody; karyopherin (importin) beta 1 antibody; Karyopherin subunit beta 1 antibody; KPNB1 antibody; NTF97 antibody; Nuclear factor p97 antibody; PTAC97 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Importin beta recombinant protein (Accession Number: NM_002265). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:111787(KPNB1 antibody) at dilution of 1:50 (under 10x lens)
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:111787(KPNB1 Antibody) at dilution of 1:600
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Background
Importin beta1, also known karyopherin beta or KPNB1, is a nuclear transport receptor that plays a key role in the nuclear import process. Importin beta1 and importin alpha work in concert to transport cargo into the nucleus, functioning as an essential component of the classical nuclear localization signal (NLS) pathway. Elevated expression of importin beta1 has been found in cervical tumors. (22125623)
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