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Product Name
IL22RA2 antibody
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Description
IL22RA2 Rabbit Polyclonal antibody. Positive FC detected in HeLa cells. Positive WB detected in MDA-MB-453s cells. Observed molecular weight by Western-blot: 27 kDa
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Tested applications
ELISA, WB, FC
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Species reactivity
Human; other species not tested.
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Alternative names
CRF2 10 antibody; CRF2 S1 antibody; CRF2X antibody; IL 22 receptor subunit alpha 2 antibody; IL 22BP antibody; IL 22R alpha 2 antibody; IL 22RA2 antibody; IL22BP antibody; IL22RA2 antibody; Interleukin 22 binding protein antibody; ZcytoR16 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of IL22RA2 recombinant protein (Accession Number: NM_181309). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with Catalog No:111780(IL22RA2 Antibody) at dilution of 1:600
1X10^6 HeLa cells were stained with 0.2ug IL22RA2 antibody (Catalog No:111780, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
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Background
Interleukin-22 receptor subunit alpha-2 (IL22RA2) is a soluble member of the type II cytokine receptor family. Through binding to IL22, IL22RA2 prevents the interaction of IL22 with the functional IL22-R complex and blocks the activity of IL22 (in vitro). IL22RA2 may play an important role as an IL22 antagonist in the regulation of inflammatory responses. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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