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Product Name
IL22RA2 antibody
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Description
IL22RA2 Mouse Monoclonal antibody. Positive IHC detected in human small intestine tissue, human breast cancer tissue, human lung cancer tissue. Positive WB detected in Raji cells. Observed molecular weight by Western-blot: 35 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
CRF2 10 antibody; CRF2 S1 antibody; CRF2X antibody; IL 22 receptor subunit alpha 2 antibody; IL 22BP antibody; IL 22R alpha 2 antibody; IL 22RA2 antibody; IL22BP antibody; IL22RA2 antibody; Interleukin 22 binding protein antibody; ZcytoR16 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of IL22RA2 recombinant protein (Accession Number: NM_181309). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Raji cells were subjected to SDS PAGE followed by western blot with Catalog No:107393(IL22RA2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using Catalog No:107393(IL22RA2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using Catalog No:107393(IL22RA2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
Interleukin-22 receptor subunit alpha-2 (IL22RA2) is a soluble member of the type II cytokine receptor family. Through binding to IL22, IL22RA2 prevents the interaction of IL22 with the functional IL22-R complex and blocks the activity of IL22 (in vitro). IL22RA2 may play an important role as an IL22 antagonist in the regulation of inflammatory responses. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"