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Product Name
IL1R2 antibody
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Description
IL1R2 Mouse Monoclonal antibody. Positive WB detected in HeLa cells. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 45KD
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Tested applications
ELISA, WB, IF
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Species reactivity
Human,Mouse; other species not tested.
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Alternative names
CD121b antibody; CDw121b antibody; IL 1R 2 antibody; IL 1R beta antibody; IL 1RT 2 antibody; IL 1RT2 antibody; IL1 Receptor 2 antibody; IL-1 Receptor 2 antibody; IL1 Receptor II antibody; IL-1 Receptor II antibody; IL1R2 antibody; IL1RB antibody; IL-1RII antibody; Interleukin 1 receptor beta antibody; Interleukin 1 receptor type 2 antibody; Interleukin 1 receptor type II antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of IL1R2 recombinant protein (Accession Number: NM_173343). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IF: 1:20-1:200
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107389(IL1R2 antibody) at dilution of 1:1000
Immunofluorescent analysis of HeLa cells using Catalog No:107389(IL1R2 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L)
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Background
Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"