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Product Name
IL17RE antibody
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Description
IL17RE Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in human kidney tissue, PC-3 cells. Observed molecular weight by Western-blot: 75 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
FLJ23658 antibody; IL 17 receptor E antibody; IL 17RE antibody; IL17RE antibody; interleukin 17 receptor E antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of IL17RE recombinant protein (Accession Number: BC063110). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:111767(IL17RE antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:111767(IL17RE antibody) at dilution of 1:50 (under 10x lens)
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Background
IL17RE, is a specific functional receptor for IL17C. It may be signaling through the NF-kappa-B and MAPK pathways. IL17Re may be a crucial regulator in innate immunity to bacterial pathogens. IL17RE has five isoforms with MW 31 kDa, 43 kDa, 58-62 kDa and 75 kDa.
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References
- Pfeifer P, Voss M, Wonnenberg B. IL-17C is a mediator of respiratory epithelial innate immune response. American journal of respiratory cell and molecular biology. 48(4):415-21. 2013.
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