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Product Name
Il17a antibody
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Description
Il17a Mouse Monoclonal antibody. Positive WB detected in Transfected HEK-293 cells.
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
Ctla 8 antibody; Ctla8 antibody; Il17 antibody; Il17a antibody; interleukin 17A antibody
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Isotype
Mouse IgG2b
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Preparation
This antibody was obtained by immunization of Il17a recombinant protein (Accession Number: NM-010552). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
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Validations
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107383(Il17a Antibody) at dilution of 1:2000
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Background
Il17a is a pro-inflammatory cytokine as a member of the interleukin-17 family. It plays a central role in host defense against diverse pathogens. It is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"